Synergistic Lysosomal Impairment and ER Stress Activation for Boosted Autophagy Dysfunction Based on Te Double‐Headed Nano‐Bullets (Small 27/2022)

Autophagy To overcome the autophagy compromised mechanism of protective cellular processes by “eating” damaged organelles or potentially toxic materials in tumor cells, Nan Li and co-workers show how tellurium double-headed nanobullets (TeDNBs)-HO is utilized to induce dysfunction. On one hand, TeDNBs-mediated endoplasmic reticulum stress could excessively autophagy; thus, resulting autophagosome accumulation. other omeprazole would deacidify impair lysosomes, therefore blocking degradation. More details can be found article number 2201585.